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Main Location of Vampyr is London of 1918. The great war is just over, the government struggles to build up the country and the Spanish Flu is spreading rapidly in this time of conflict.

Mentioned in their Webseries: DONTNOD Presents Vampyr Episode 2 - Architects of the Obscure are Whitechapel, East End Docks, West End and the Poplar Hospital, where player character Jonathan E. Reid works as a surgeon.